BDBM50068315 3-Diethylamino-N-[8-(3-diethylamino-propionylamino)-9,10-dioxo-9,10-dihydro-anthracen-1-yl]-propionamide::CHEMBL145575

SMILES: CCN(CC)CCC(=O)Nc1cccc2C(=O)c3cccc(NC(=O)CCN(CC)CC)c3C(=O)c12

InChI Key: InChIKey=DHHZSQSAPLVDAV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50068315 (3-Diethylamino-N-[8-(3-diethylamino-propionylamino...) Show SMILES CCN(CC)CCC(=O)Nc1cccc2C(=O)c3cccc(NC(=O)CCN(CC)CC)c3C(=O)c12 Show InChI InChI=1S/C28H36N4O4/c1-5-31(6-2)17-15-23(33)29-21-13-9-11-19-25(21)28(36)26-20(27(19)35)12-10-14-22(26)30-24(34)16-18-32(7-3)8-4/h9-14H,5-8,15-18H2,1-4H3,(H,29,33)(H,30,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibitory activity of telomerase was measured using the TRAP assay.				J Med Chem 41: 4873-84 (1998) Article DOI: 10.1021/jm981067o BindingDB Entry DOI: 10.7270/Q2WW7GSD
					More data for this Ligand-Target Pair