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BDBM50068383 CHEMBL3402344

SMILES: CC(C)C(=O)N1N=C(SC11CCOc2ccccc12)c1cc(F)ccc1F

InChI Key: InChIKey=YRLNTHMQFJTNJT-UHFFFAOYNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068383   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens)
BDBM50068383
PNG
(CHEMBL3402344)
Show SMILES CC(C)C(=O)N1N=C(SC11CCOc2ccccc12)c1cc(F)ccc1F
Show InChI InChI=1/C20H18F2N2O2S/c1-12(2)19(25)24-20(9-10-26-17-6-4-3-5-15(17)20)27-18(23-24)14-11-13(21)7-8-16(14)22/h3-8,11-12H,9-10H2,1-2H3
PDB
MMDB

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Similars

Article
PubMed
n/an/an/an/a>500n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of KSP in human HCT116 cells assessed as phos-histone H3 level by immunofluorescent assay


Bioorg Med Chem 23: 2424-34 (2015)

More data for this
Ligand-Target Pair