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BDBM50068386 CHEMBL3402347

SMILES: COCC(=O)N1N=C(SC11CCOc2ccccc12)c1cc(F)ccc1F

InChI Key: InChIKey=QGQBTWIQMUMLAZ-UHFFFAOYNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068386   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens)
BDBM50068386
PNG
(CHEMBL3402347)
Show SMILES COCC(=O)N1N=C(SC11CCOc2ccccc12)c1cc(F)ccc1F
Show InChI InChI=1/C19H16F2N2O3S/c1-25-11-17(24)23-19(8-9-26-16-5-3-2-4-14(16)19)27-18(22-23)13-10-12(20)6-7-15(13)21/h2-7,10H,8-9,11H2,1H3
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MMDB

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Similars

Article
PubMed
n/an/an/an/a 665n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of KSP in human HCT116 cells assessed as phos-histone H3 level by immunofluorescent assay


Bioorg Med Chem 23: 2424-34 (2015)

More data for this
Ligand-Target Pair