BDBM50068450 1-[2-(2-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)-piperazine::CHEMBL147779

SMILES: COc1ccccc1CCN1CCN(CCCc2ccccc2)CC1

InChI Key: InChIKey=VXHNZWJDUQQSEQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50068450 (1-[2-(2-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...) Show SMILES COc1ccccc1CCN1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C22H30N2O/c1-25-22-12-6-5-11-21(22)13-15-24-18-16-23(17-19-24)14-7-10-20-8-3-2-4-9-20/h2-6,8-9,11-12H,7,10,13-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysis				Bioorg Med Chem 23: 222-30 (2014) Article DOI: 10.1016/j.bmc.2014.11.007 BindingDB Entry DOI: 10.7270/Q2KH0PXF
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068450 (1-[2-(2-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...) Show SMILES COc1ccccc1CCN1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C22H30N2O/c1-25-22-12-6-5-11-21(22)13-15-24-18-16-23(17-19-24)14-7-10-20-8-3-2-4-9-20/h2-6,8-9,11-12H,7,10,13-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair