BDBM50068455 CHEMBL342809::{4-Oxo-4-[4-(3-phenyl-propyl)-piperazin-1-yl]-butyl}-carbamic acid tert-butyl ester

SMILES: CC(C)(C)OC(=O)NCCCC(=O)N1CCN(CCCc2ccccc2)CC1

InChI Key: InChIKey=DLYIENCMFCRKMN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068455 (CHEMBL342809 | {4-Oxo-4-[4-(3-phenyl-propyl)-piper...) Show SMILES CC(C)(C)OC(=O)NCCCC(=O)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C22H35N3O3/c1-22(2,3)28-21(27)23-13-7-12-20(26)25-17-15-24(16-18-25)14-8-11-19-9-5-4-6-10-19/h4-6,9-10H,7-8,11-18H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair