BDBM50068514 2-(5-Fluoro-1H-indol-3-yl)-cyclopropylamine::CHEMBL147656

SMILES: NC1CC1c1c[nH]c2ccc(F)cc12

InChI Key: InChIKey=CFGZJSVULAXTDM-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50068514 (2-(5-Fluoro-1H-indol-3-yl)-cyclopropylamine | CHEM...) Show SMILES NC1CC1c1c[nH]c2ccc(F)cc12 Show InChI InChI=1S/C11H11FN2/c12-6-1-2-11-8(3-6)9(5-14-11)7-4-10(7)13/h1-3,5,7,10,14H,4,13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against the cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand				J Med Chem 41: 4995-5001 (1999) Article DOI: 10.1021/jm980318q BindingDB Entry DOI: 10.7270/Q2HQ3Z24
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50068514 (2-(5-Fluoro-1H-indol-3-yl)-cyclopropylamine | CHEM...) Show SMILES NC1CC1c1c[nH]c2ccc(F)cc12 Show InChI InChI=1S/C11H11FN2/c12-6-1-2-11-8(3-6)9(5-14-11)7-4-10(7)13/h1-3,5,7,10,14H,4,13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against the cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT as the radioligand				J Med Chem 41: 4995-5001 (1999) Article DOI: 10.1021/jm980318q BindingDB Entry DOI: 10.7270/Q2HQ3Z24
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50068514 (2-(5-Fluoro-1H-indol-3-yl)-cyclopropylamine | CHEM...) Show SMILES NC1CC1c1c[nH]c2ccc(F)cc12 Show InChI InChI=1S/C11H11FN2/c12-6-1-2-11-8(3-6)9(5-14-11)7-4-10(7)13/h1-3,5,7,10,14H,4,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against the cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as the radioligand				J Med Chem 41: 4995-5001 (1999) Article DOI: 10.1021/jm980318q BindingDB Entry DOI: 10.7270/Q2HQ3Z24
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50068514 (2-(5-Fluoro-1H-indol-3-yl)-cyclopropylamine | CHEM...) Show SMILES NC1CC1c1c[nH]c2ccc(F)cc12 Show InChI InChI=1S/C11H11FN2/c12-6-1-2-11-8(3-6)9(5-14-11)7-4-10(7)13/h1-3,5,7,10,14H,4,13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	258	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against the 5-hydroxytryptamine 1A receptor labelled with [3H]-8-OH-DPAT in rat hippocampal homogenates				J Med Chem 41: 4995-5001 (1999) Article DOI: 10.1021/jm980318q BindingDB Entry DOI: 10.7270/Q2HQ3Z24
					More data for this Ligand-Target Pair