BDBM50068516 2-(5-Methoxy-1H-indol-3-yl)-propylamine::CHEMBL149564
SMILES: COc1ccc2[nH]cc(C(C)CN)c2c1
InChI Key: InChIKey=PLKJXFPRSHOODN-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50068516 (2-(5-Methoxy-1H-indol-3-yl)-propylamine | CHEMBL14...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Binding affinity against the cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand | J Med Chem 41: 4995-5001 (1999) Article DOI: 10.1021/jm980318q BindingDB Entry DOI: 10.7270/Q2HQ3Z24 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50068516 (2-(5-Methoxy-1H-indol-3-yl)-propylamine | CHEMBL14...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Binding affinity against the cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as the radioligand | J Med Chem 41: 4995-5001 (1999) Article DOI: 10.1021/jm980318q BindingDB Entry DOI: 10.7270/Q2HQ3Z24 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50068516 (2-(5-Methoxy-1H-indol-3-yl)-propylamine | CHEMBL14...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Binding affinity against the cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT as the radioligand | J Med Chem 41: 4995-5001 (1999) Article DOI: 10.1021/jm980318q BindingDB Entry DOI: 10.7270/Q2HQ3Z24 | |||||||||||
More data for this Ligand-Target Pair |