BDBM50068692 2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-isobutyl-biphenyl-2-carboxylic acid amide::CHEMBL146904

SMILES: CC(C)Cc1ccc(c(c1)C(N)=O)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C

InChI Key: InChIKey=MCLUDZBONQYSJK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRA (RAT)	BDBM50068692 (2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-isobuty...) Show SMILES CC(C)Cc1ccc(c(c1)C(N)=O)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C22H25N3O4S/c1-13(2)11-16-9-10-17(19(12-16)21(23)26)18-7-5-6-8-20(18)30(27,28)25-22-14(3)15(4)24-29-22/h5-10,12-13,25H,11H2,1-4H3,(H2,23,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptor				J Med Chem 41: 5198-218 (1999) Article DOI: 10.1021/jm970872k BindingDB Entry DOI: 10.7270/Q2J9672R
					More data for this Ligand-Target Pair
EDNRB (RAT)	BDBM50068692 (2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-isobuty...) Show SMILES CC(C)Cc1ccc(c(c1)C(N)=O)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C22H25N3O4S/c1-13(2)11-16-9-10-17(19(12-16)21(23)26)18-7-5-6-8-20(18)30(27,28)25-22-14(3)15(4)24-29-22/h5-10,12-13,25H,11H2,1-4H3,(H2,23,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Ability to inhibit binding of [125I]-ET-1 to membranes prepared from A10 rat cerebellum (Endothelin B receptor)				J Med Chem 41: 5198-218 (1999) Article DOI: 10.1021/jm970872k BindingDB Entry DOI: 10.7270/Q2J9672R
					More data for this Ligand-Target Pair