Found 4 hits for monomerid = 50068983 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Coagulation factor VII
(Homo sapiens (Human)) | BDBM50068983
(CHEMBL3400183)Show SMILES CCOc1cc(OC(C)C)c(F)c(c1)C(Nc1ccc(cc1)C(N)=N)c1nc(c[nH]1)-c1ccccc1C(O)=O Show InChI InChI=1S/C29H30FN5O4/c1-4-38-19-13-22(25(30)24(14-19)39-16(2)3)26(34-18-11-9-17(10-12-18)27(31)32)28-33-15-23(35-28)20-7-5-6-8-21(20)29(36)37/h5-16,26,34H,4H2,1-3H3,(H3,31,32)(H,33,35)(H,36,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D
Curated by ChEMBL
| Assay Description
Inhibition of human factor 7a using H-D-Ile-Pro-Arg-pNA substrate |
Bioorg Med Chem Lett 25: 2169-73 (2015)
Article DOI: 10.1016/j.bmcl.2015.03.062
BindingDB Entry DOI: 10.7270/Q2GQ70FP |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50068983
(CHEMBL3400183)Show SMILES CCOc1cc(OC(C)C)c(F)c(c1)C(Nc1ccc(cc1)C(N)=N)c1nc(c[nH]1)-c1ccccc1C(O)=O Show InChI InChI=1S/C29H30FN5O4/c1-4-38-19-13-22(25(30)24(14-19)39-16(2)3)26(34-18-11-9-17(10-12-18)27(31)32)28-33-15-23(35-28)20-7-5-6-8-21(20)29(36)37/h5-16,26,34H,4H2,1-3H3,(H3,31,32)(H,33,35)(H,36,37) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D
Curated by ChEMBL
| Assay Description
Inhibition of factor 2a (unknown origin) |
Bioorg Med Chem Lett 25: 2169-73 (2015)
Article DOI: 10.1016/j.bmcl.2015.03.062
BindingDB Entry DOI: 10.7270/Q2GQ70FP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50068983
(CHEMBL3400183)Show SMILES CCOc1cc(OC(C)C)c(F)c(c1)C(Nc1ccc(cc1)C(N)=N)c1nc(c[nH]1)-c1ccccc1C(O)=O Show InChI InChI=1S/C29H30FN5O4/c1-4-38-19-13-22(25(30)24(14-19)39-16(2)3)26(34-18-11-9-17(10-12-18)27(31)32)28-33-15-23(35-28)20-7-5-6-8-21(20)29(36)37/h5-16,26,34H,4H2,1-3H3,(H3,31,32)(H,33,35)(H,36,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D
Curated by ChEMBL
| Assay Description
Inhibition of factor 10a (unknown origin) |
Bioorg Med Chem Lett 25: 2169-73 (2015)
Article DOI: 10.1016/j.bmcl.2015.03.062
BindingDB Entry DOI: 10.7270/Q2GQ70FP |
More data for this
Ligand-Target Pair | |
Trypsin
(Homo sapiens (Human)) | BDBM50068983
(CHEMBL3400183)Show SMILES CCOc1cc(OC(C)C)c(F)c(c1)C(Nc1ccc(cc1)C(N)=N)c1nc(c[nH]1)-c1ccccc1C(O)=O Show InChI InChI=1S/C29H30FN5O4/c1-4-38-19-13-22(25(30)24(14-19)39-16(2)3)26(34-18-11-9-17(10-12-18)27(31)32)28-33-15-23(35-28)20-7-5-6-8-21(20)29(36)37/h5-16,26,34H,4H2,1-3H3,(H3,31,32)(H,33,35)(H,36,37) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D
Curated by ChEMBL
| Assay Description
Inhibition of trypsin (unknown origin) |
Bioorg Med Chem Lett 25: 2169-73 (2015)
Article DOI: 10.1016/j.bmcl.2015.03.062
BindingDB Entry DOI: 10.7270/Q2GQ70FP |
More data for this
Ligand-Target Pair | |
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