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SMILES: C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2[C@H]1C)C(F)(F)F

InChI Key: InChIKey=JEKLOWJNFQMNLW-NKWVEPMBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50069065 ((2R,3R)-2,3-Dimethyl-5-trifluoromethyl-1,2,3,8-tet...) Show SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2[C@H]1C)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O/c1-6-7(2)18-11-5-12-9(3-8(6)11)10(14(15,16)17)4-13(20)19-12/h3-7,18H,1-2H3,(H,19,20)/t6-,7+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against Androgen receptor transfected into COS cells				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50069065 ((2R,3R)-2,3-Dimethyl-5-trifluoromethyl-1,2,3,8-tet...) Show SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2[C@H]1C)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O/c1-6-7(2)18-11-5-12-9(3-8(6)11)10(14(15,16)17)4-13(20)19-12/h3-7,18H,1-2H3,(H,19,20)/t6-,7+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Agonistic activity (EC50) against human androgen receptor (hAR) in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50069065 ((2R,3R)-2,3-Dimethyl-5-trifluoromethyl-1,2,3,8-tet...) Show SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2[C@H]1C)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O/c1-6-7(2)18-11-5-12-9(3-8(6)11)10(14(15,16)17)4-13(20)19-12/h3-7,18H,1-2H3,(H,19,20)/t6-,7+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against hMR in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50069065 ((2R,3R)-2,3-Dimethyl-5-trifluoromethyl-1,2,3,8-tet...) Show SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2[C@H]1C)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O/c1-6-7(2)18-11-5-12-9(3-8(6)11)10(14(15,16)17)4-13(20)19-12/h3-7,18H,1-2H3,(H,19,20)/t6-,7+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against hAR androgen receptor expressed in COS cells				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50069065 ((2R,3R)-2,3-Dimethyl-5-trifluoromethyl-1,2,3,8-tet...) Show SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2[C@H]1C)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O/c1-6-7(2)18-11-5-12-9(3-8(6)11)10(14(15,16)17)4-13(20)19-12/h3-7,18H,1-2H3,(H,19,20)/t6-,7+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against hPR in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50069065 ((2R,3R)-2,3-Dimethyl-5-trifluoromethyl-1,2,3,8-tet...) Show SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2[C@H]1C)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O/c1-6-7(2)18-11-5-12-9(3-8(6)11)10(14(15,16)17)4-13(20)19-12/h3-7,18H,1-2H3,(H,19,20)/t6-,7+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against Glucocorticoid receptor in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair