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SMILES: Cn1c2cc3N[C@@H]4CCCC[C@@H]4c3cc2c(cc1=O)C(F)(F)F

InChI Key: InChIKey=YXFRGFFRCABTFT-NOZJJQNGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50069069 ((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...) Show SMILES Cn1c2cc3N[C@@H]4CCCC[C@@H]4c3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O/c1-22-15-8-14-10(9-4-2-3-5-13(9)21-14)6-11(15)12(7-16(22)23)17(18,19)20/h6-9,13,21H,2-5H2,1H3/t9-,13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against Androgen receptor transfected into COS cells				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50069069 ((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...) Show SMILES Cn1c2cc3N[C@@H]4CCCC[C@@H]4c3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O/c1-22-15-8-14-10(9-4-2-3-5-13(9)21-14)6-11(15)12(7-16(22)23)17(18,19)20/h6-9,13,21H,2-5H2,1H3/t9-,13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Agonistic activity (EC50) against human androgen receptor (hAR) in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50069069 ((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...) Show SMILES Cn1c2cc3N[C@@H]4CCCC[C@@H]4c3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O/c1-22-15-8-14-10(9-4-2-3-5-13(9)21-14)6-11(15)12(7-16(22)23)17(18,19)20/h6-9,13,21H,2-5H2,1H3/t9-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against hMR in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50069069 ((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...) Show SMILES Cn1c2cc3N[C@@H]4CCCC[C@@H]4c3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O/c1-22-15-8-14-10(9-4-2-3-5-13(9)21-14)6-11(15)12(7-16(22)23)17(18,19)20/h6-9,13,21H,2-5H2,1H3/t9-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against Androgen receptor transfected into COS cells				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50069069 ((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...) Show SMILES Cn1c2cc3N[C@@H]4CCCC[C@@H]4c3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O/c1-22-15-8-14-10(9-4-2-3-5-13(9)21-14)6-11(15)12(7-16(22)23)17(18,19)20/h6-9,13,21H,2-5H2,1H3/t9-,13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against Glucocorticoid receptor in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50069069 ((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...) Show SMILES Cn1c2cc3N[C@@H]4CCCC[C@@H]4c3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O/c1-22-15-8-14-10(9-4-2-3-5-13(9)21-14)6-11(15)12(7-16(22)23)17(18,19)20/h6-9,13,21H,2-5H2,1H3/t9-,13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against hPR in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair