null
SMILES: Cc1ccc(NCCc2ccccc2)c(=O)n1CC(=O)NC[C@H]1CC[C@H](N)CC1
InChI Key: InChIKey=SFAAKBBANQLWSZ-MXVIHJGJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50069193 (CHEMBL424545 | N-(4-Amino-cyclohexylmethyl)-2-(6-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards thrombin was evaluated | Bioorg Med Chem Lett 8: 817-22 (1999) BindingDB Entry DOI: 10.7270/Q2JH3K9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50069193 (CHEMBL424545 | N-(4-Amino-cyclohexylmethyl)-2-(6-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against human thrombin | Bioorg Med Chem Lett 7: 1497-1500 (1997) Article DOI: 10.1016/S0960-894X(97)00257-6 BindingDB Entry DOI: 10.7270/Q2P55P15 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50069193 (CHEMBL424545 | N-(4-Amino-cyclohexylmethyl)-2-(6-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against human trypsin | Bioorg Med Chem Lett 7: 1497-1500 (1997) Article DOI: 10.1016/S0960-894X(97)00257-6 BindingDB Entry DOI: 10.7270/Q2P55P15 | |||||||||||
More data for this Ligand-Target Pair |