BDBM50069223 (2R,3R)-3-Benzyl-2,N*1*-dihydroxy-N*4*-[(S)-2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-2-methyl-succinamide::CHEMBL435271

SMILES: CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](Cc1ccccc1)[C@@](C)(O)C(=O)NO

InChI Key: InChIKey=NKAFEKVEMSYZIX-SFYKDHMMSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50069223 ((2R,3R)-3-Benzyl-2,N*1*-dihydroxy-N*4*-[(S)-2-(4-m...) Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](Cc1ccccc1)[C@@](C)(O)C(=O)NO Show InChI InChI=1S/C23H29N3O6/c1-23(30,22(29)26-31)18(13-15-7-5-4-6-8-15)20(27)25-19(21(28)24-2)14-16-9-11-17(32-3)12-10-16/h4-12,18-19,30-31H,13-14H2,1-3H3,(H,24,28)(H,25,27)(H,26,29)/t18-,19-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Binding affinity was evaluated against matrix metalloproteinase-9				Bioorg Med Chem Lett 8: 837-42 (1999) BindingDB Entry DOI: 10.7270/Q29022WN
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50069223 ((2R,3R)-3-Benzyl-2,N*1*-dihydroxy-N*4*-[(S)-2-(4-m...) Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](Cc1ccccc1)[C@@](C)(O)C(=O)NO Show InChI InChI=1S/C23H29N3O6/c1-23(30,22(29)26-31)18(13-15-7-5-4-6-8-15)20(27)25-19(21(28)24-2)14-16-9-11-17(32-3)12-10-16/h4-12,18-19,30-31H,13-14H2,1-3H3,(H,24,28)(H,25,27)(H,26,29)/t18-,19-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Binding affinity was evaluated against matrix metalloproteinase-1				Bioorg Med Chem Lett 8: 837-42 (1999) BindingDB Entry DOI: 10.7270/Q29022WN
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50069223 ((2R,3R)-3-Benzyl-2,N*1*-dihydroxy-N*4*-[(S)-2-(4-m...) Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](Cc1ccccc1)[C@@](C)(O)C(=O)NO Show InChI InChI=1S/C23H29N3O6/c1-23(30,22(29)26-31)18(13-15-7-5-4-6-8-15)20(27)25-19(21(28)24-2)14-16-9-11-17(32-3)12-10-16/h4-12,18-19,30-31H,13-14H2,1-3H3,(H,24,28)(H,25,27)(H,26,29)/t18-,19-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	526	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Binding affinity against human matrix metalloproteinase-3.				Bioorg Med Chem Lett 8: 837-42 (1999) BindingDB Entry DOI: 10.7270/Q29022WN
					More data for this Ligand-Target Pair