BDBM50069273 (Z)-1,1,1-Trifluoro-nonadec-10-en-2-one::1,1,1-trifluorononadec-10-en-2-one::CHEMBL422064
SMILES: CCCCCCCC\C=C/CCCCCCCC(=O)C(F)(F)F
InChI Key: InChIKey=SOJGXPSMVNTNQL-KTKRTIGZSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain Curated by ChEMBL | Assay Description Binding affinity for fatty acid amide hydrolase | J Med Chem 48: 5059-87 (2005) Article DOI: 10.1021/jm058183t BindingDB Entry DOI: 10.7270/Q2J96753 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of FAAH | Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Inhibition of FAAH | J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli | J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Scripps Research Institute Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Fatty-acid amide hydrolase (FAAH) in rat liver | Bioorg Med Chem Lett 9: 265-70 (1999) BindingDB Entry DOI: 10.7270/Q2CR5SJ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of rat FAAH assessed as conversion [14]C-oleamide to oleic acid | Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology Curated by ChEMBL | Assay Description Compound was tested for inhibitory potency against Fatty-acid amide hydrolase (FAAH) at pH 9.0 | Bioorg Med Chem Lett 8: 613-8 (1999) BindingDB Entry DOI: 10.7270/Q2HH6J61 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibitory concentration against Fatty-acid amide hydrolase | J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibitory concentration against Triacylglycerol hydrolase | J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibitory concentration against Fatty-acid amide hydrolase (FAAH) at pH 9.0 | Bioorg Med Chem Lett 8: 613-8 (1999) BindingDB Entry DOI: 10.7270/Q2HH6J61 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Scripps Research Institute Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Fatty-acid amide hydrolase (FAAH) in rat liver | Bioorg Med Chem Lett 9: 265-70 (1999) BindingDB Entry DOI: 10.7270/Q2CR5SJ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50069273 ((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibitory concentration against Fatty-acid amide hydrolase (FAAH) at pH 9.0 | Bioorg Med Chem Lett 8: 613-8 (1999) BindingDB Entry DOI: 10.7270/Q2HH6J61 | |||||||||||
More data for this Ligand-Target Pair |