BDBM50069597 (2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*-hydroxy-2-isobutyl-3-(thiophen-2-ylsulfanylmethyl)-succinamide::CHEMBL424251

SMILES: CC(C)C[C@H]([C@H](CSc1cccs1)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key: InChIKey=ZCJSXQVUNXJVQQ-SQNIBIBYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Immunoglobulin epsilon Fc receptor (Homo sapiens (Human))	BDBM50069597 ((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...) Show SMILES CC(C)C[C@H]([C@H](CSc1cccs1)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C22H29N3O4S2/c1-14(2)11-16(17(22(28)25-29)13-31-19-9-6-10-30-19)21(27)24-18(20(23)26)12-15-7-4-3-5-8-15/h3-10,14,16-18,29H,11-13H2,1-2H3,(H2,23,26)(H,24,27)(H,25,28)/t16-,17+,18+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells				Bioorg Med Chem Lett 8: 29-34 (1999) BindingDB Entry DOI: 10.7270/Q2TT4Q3W
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50069597 ((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...) Show SMILES CC(C)C[C@H]([C@H](CSc1cccs1)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C22H29N3O4S2/c1-14(2)11-16(17(22(28)25-29)13-31-19-9-6-10-30-19)21(27)24-18(20(23)26)12-15-7-4-3-5-8-15/h3-10,14,16-18,29H,11-13H2,1-2H3,(H2,23,26)(H,24,27)(H,25,28)/t16-,17+,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity of the compound towards human recombinant fibroblast collagenase				Bioorg Med Chem Lett 8: 29-34 (1999) BindingDB Entry DOI: 10.7270/Q2TT4Q3W
					More data for this Ligand-Target Pair