BDBM50069609 (2R,3S)-2-{2-Biphenyl-4-yl-2-[(E)-hydroxyimino]-ethylsulfanylmethyl}-N*1*-hydroxy-3-isobutyl-N*4*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide::CHEMBL114332

SMILES: CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSCC(N=O)c1ccc(cc1)-c1ccccc1)C(=O)NO

InChI Key: InChIKey=VUOYXAHTJMIVRD-VRLMGCJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Immunoglobulin epsilon Fc receptor (Homo sapiens (Human))	BDBM50069609 ((2R,3S)-2-{2-Biphenyl-4-yl-2-[(E)-hydroxyimino]-et...) Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSCC(N=O)c1ccc(cc1)-c1ccccc1)C(=O)NO Show InChI InChI=1S/C33H40N4O5S/c1-22(2)18-27(31(38)35-29(33(40)34-3)19-23-10-6-4-7-11-23)28(32(39)37-42)20-43-21-30(36-41)26-16-14-25(15-17-26)24-12-8-5-9-13-24/h4-17,22,27-30,42H,18-21H2,1-3H3,(H,34,40)(H,35,38)(H,37,39)/t27-,28+,29+,30?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells				Bioorg Med Chem Lett 8: 29-34 (1999) BindingDB Entry DOI: 10.7270/Q2TT4Q3W
					More data for this Ligand-Target Pair