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BDBM50069829 5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-nicotinic acid methyl ester::CHEMBL85755

SMILES: COC(=O)c1cncc(OC[C@@H]2CCCN2C)c1

InChI Key: InChIKey=SYEVEORWRHDXTI-NSHDSACASA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069829   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Rattus norvegicus (Rat))		BDBM50069829
PNG
(5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-nicotinic ...)
Show SMILES COC(=O)c1cncc(OC[C@@H]2CCCN2C)c1
Show InChI InChI=1S/C13H18N2O3/c1-15-5-3-4-11(15)9-18-12-6-10(7-14-8-12)13(16)17-2/h6-8,11H,3-5,9H2,1-2H3/t11-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
PubMed
 1.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards nAChR (alpha4-beta2) by the displacement of [3H]-(-)-cytisine in whole rat brain membranes.

Bioorg Med Chem Lett 8: 249-54 (1999)


BindingDB Entry DOI: 10.7270/Q2P26X90
More data for this
Ligand-Target Pair