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SMILES: [O-]C(=O)c1c2CCc3cc(ccc3-c2nc2ccc(F)cc12)-c1nccs1

InChI Key: InChIKey=YCMOPLZNEBCFEK-UHFFFAOYSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069942   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50069942
PNG
(CHEMBL107417 | Sodium; 9-fluoro-3-thiazol-2-yl-5,6...)
Show SMILES [O-]C(=O)c1c2CCc3cc(ccc3-c2nc2ccc(F)cc12)-c1nccs1
Show InChI InChI=1S/C21H13FN2O2S/c22-13-3-6-17-16(10-13)18(21(25)26)15-5-1-11-9-12(20-23-7-8-27-20)2-4-14(11)19(15)24-17/h2-4,6-10H,1,5H2,(H,25,26)/p-1
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PubMed
>180n/an/an/an/an/an/an/an/a



DuPont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)

Bioorg Med Chem Lett 8: 307-12 (1999)


BindingDB Entry DOI: 10.7270/Q21C1W19
More data for this
Ligand-Target Pair