BDBM50070294 CHEMBL20165::N-[3-Hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl]-2-(4-hydroxy-2-methyl-pyrrolidin-2-yl)-acetamide

SMILES: Cc1cn(C2CC(O)C(CNC(=O)CC3(C)CC(O)CN3)O2)c(=O)[nH]c1=O

InChI Key: InChIKey=QQJZDXXMFYEMRX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50070294 (CHEMBL20165 | N-[3-Hydroxy-5-(5-methyl-2,4-dioxo-3...) Show SMILES Cc1cn(C2CC(O)C(CNC(=O)CC3(C)CC(O)CN3)O2)c(=O)[nH]c1=O Show InChI InChI=1S/C17H26N4O6/c1-9-8-21(16(26)20-15(9)25)14-3-11(23)12(27-14)7-18-13(24)5-17(2)4-10(22)6-19-17/h8,10-12,14,19,22-23H,3-7H2,1-2H3,(H,18,24)(H,20,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Wales Cardiff Curated by ChEMBL					Assay Description Concentration required for no significant inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 8: 1211-4 (1999) BindingDB Entry DOI: 10.7270/Q2PZ580P
					More data for this Ligand-Target Pair