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SMILES: CC(C)Oc1nn(c(C)c1C(O)c1ccccc1)-c1ncc(cn1)C1CC1

InChI Key: InChIKey=BSNKBAPMWCMENP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070906   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50070906
PNG
(CHEMBL3409299)
Show SMILES CC(C)Oc1nn(c(C)c1C(O)c1ccccc1)-c1ncc(cn1)C1CC1
Show InChI InChI=1S/C21H24N4O2/c1-13(2)27-20-18(19(26)16-7-5-4-6-8-16)14(3)25(24-20)21-22-11-17(12-23-21)15-9-10-15/h4-8,11-13,15,19,26H,9-10H2,1-3H3
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MMDB

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Institut Pasteur

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometry

J Med Chem 58: 860-77 (2015)


Article DOI: 10.1021/jm501446r
BindingDB Entry DOI: 10.7270/Q2K9396J
More data for this
Ligand-Target Pair