BDBM50070946 1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexahydropyridine)]-7-ol::CHEMBL300689

SMILES: CC1CN(C)CCC11COc2c1cccc2O

InChI Key: InChIKey=BQENLWFUKSDROS-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50070946 (1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...) Show SMILES CC1CN(C)CCC11COc2c1cccc2O Show InChI InChI=1S/C14H19NO2/c1-10-8-15(2)7-6-14(10)9-17-13-11(14)4-3-5-12(13)16/h3-5,10,16H,6-9H2,1-2H3	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigs				Bioorg Med Chem Lett 8: 1813-8 (1999) BindingDB Entry DOI: 10.7270/Q2K073D5
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50070946 (1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...) Show SMILES CC1CN(C)CCC11COc2c1cccc2O Show InChI InChI=1S/C14H19NO2/c1-10-8-15(2)7-6-14(10)9-17-13-11(14)4-3-5-12(13)16/h3-5,10,16H,6-9H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigs				Bioorg Med Chem Lett 8: 1813-8 (1999) BindingDB Entry DOI: 10.7270/Q2K073D5
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50070946 (1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...) Show SMILES CC1CN(C)CCC11COc2c1cccc2O Show InChI InChI=1S/C14H19NO2/c1-10-8-15(2)7-6-14(10)9-17-13-11(14)4-3-5-12(13)16/h3-5,10,16H,6-9H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	505	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigs				Bioorg Med Chem Lett 8: 1813-8 (1999) BindingDB Entry DOI: 10.7270/Q2K073D5
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50070946 (1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...) Show SMILES CC1CN(C)CCC11COc2c1cccc2O Show InChI InChI=1S/C14H19NO2/c1-10-8-15(2)7-6-14(10)9-17-13-11(14)4-3-5-12(13)16/h3-5,10,16H,6-9H2,1-2H3	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigs				Bioorg Med Chem Lett 8: 1813-8 (1999) BindingDB Entry DOI: 10.7270/Q2K073D5
					More data for this Ligand-Target Pair