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BDBM50071013 CHEMBL3409546

SMILES: [Br-].CC1(C)\C(=C/C=C/C2=[N+](CCCc3ccccc3)c3ccc(Cl)cc3C2(C)C)N(CCCc2ccccc2)c2ccc(Cl)cc12

InChI Key: InChIKey=SNASIPHDQMTNOG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071013   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-arginine N-methyltransferase 1


(Homo sapiens (Human))		BDBM50071013
PNG
(CHEMBL3409546)
Show SMILES [Br-].CC1(C)\C(=C/C=C/C2=[N+](CCCc3ccccc3)c3ccc(Cl)cc3C2(C)C)N(CCCc2ccccc2)c2ccc(Cl)cc12 |c:7|
Show InChI InChI=1S/C41H43Cl2N2/c1-40(2)34-28-32(42)22-24-36(34)44(26-12-18-30-14-7-5-8-15-30)38(40)20-11-21-39-41(3,4)35-29-33(43)23-25-37(35)45(39)27-13-19-31-16-9-6-10-17-31/h5-11,14-17,20-25,28-29H,12-13,18-19,26-27H2,1-4H3/q+1
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Similars
Article
PubMed
n/an/a 1.15E+3n/an/an/an/an/an/a



The University of Georgia

Curated by ChEMBL


Assay Description
Displacement of [3H]-SAM from recombinant His6-tagged PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) incubated for 5 mins prior to H4...

J Med Chem 58: 1228-43 (2015)


Article DOI: 10.1021/jm501452j
BindingDB Entry DOI: 10.7270/Q29S1SQN
More data for this
Ligand-Target Pair