BDBM50071137 (Z)-7-{3-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-dihydro-oxazol-2-yl]-phenyl}-7-pyridin-3-yl-hept-6-enoic acid::CHEMBL294850

SMILES: OC(=O)CCCC\C=C(/c1cccnc1)c1cccc(c1)C1=N[C@H](CO1)C(=O)NCCCCC1CCCCC1

InChI Key: InChIKey=IUIKKXJIHSJKKO-FHGOPSEHSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50071137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50071137 ((Z)-7-{3-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...) Show SMILES OC(=O)CCCC\C=C(/c1cccnc1)c1cccc(c1)C1=N[C@H](CO1)C(=O)NCCCCC1CCCCC1 |t:23| Show InChI InChI=1S/C32H41N3O4/c36-30(37)18-6-2-5-17-28(27-16-10-19-33-22-27)25-14-9-15-26(21-25)32-35-29(23-39-32)31(38)34-20-8-7-13-24-11-3-1-4-12-24/h9-10,14-17,19,21-22,24,29H,1-8,11-13,18,20,23H2,(H,34,38)(H,36,37)/b28-17-/t29-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro thromboxane receptor antagonism was determined using a human platelet binding assay				Bioorg Med Chem Lett 8: 1943-8 (1999) BindingDB Entry DOI: 10.7270/Q2DB8107
					More data for this Ligand-Target Pair
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50071137 ((Z)-7-{3-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...) Show SMILES OC(=O)CCCC\C=C(/c1cccnc1)c1cccc(c1)C1=N[C@H](CO1)C(=O)NCCCCC1CCCCC1 |t:23| Show InChI InChI=1S/C32H41N3O4/c36-30(37)18-6-2-5-17-28(27-16-10-19-33-22-27)25-14-9-15-26(21-25)32-35-29(23-39-32)31(38)34-20-8-7-13-24-11-3-1-4-12-24/h9-10,14-17,19,21-22,24,29H,1-8,11-13,18,20,23H2,(H,34,38)(H,36,37)/b28-17-/t29-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	452	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2				Bioorg Med Chem Lett 8: 1943-8 (1999) BindingDB Entry DOI: 10.7270/Q2DB8107
					More data for this Ligand-Target Pair