BDBM50071321 CHEMBL3410000

SMILES: Cc1c(Br)cc(cc1S(=O)(=O)NC1CCCC1)-c1csc(=O)[nH]1

InChI Key: InChIKey=CGVZMKABKWWTHX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071321   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50071321 (CHEMBL3410000) Show SMILES Cc1c(Br)cc(cc1S(=O)(=O)NC1CCCC1)-c1csc(=O)[nH]1 Show InChI InChI=1S/C15H17BrN2O3S2/c1-9-12(16)6-10(13-8-22-15(19)17-13)7-14(9)23(20,21)18-11-4-2-3-5-11/h6-8,11,18H,2-5H2,1H3,(H,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of BRD4(1) (unknown origin) incubated for 4 hrs by (+)-JQ1 fluorescent ligand based fluorescence anisotrophy				J Med Chem 58: 1281-97 (2015) Article DOI: 10.1021/jm501504k BindingDB Entry DOI: 10.7270/Q2P270TX
					More data for this Ligand-Target Pair