BDBM50071339 CHEMBL68475::N-[4-(1H-Imidazol-4-yl)-butyl]-4-trifluoromethoxy-benzenesulfonamide

SMILES: FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCc1cnc[nH]1

InChI Key: InChIKey=TWPHREBKJNHZKY-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HRH3 (GUINEA PIG)	BDBM50071339 (CHEMBL68475 | N-[4-(1H-Imidazol-4-yl)-butyl]-4-tri...) Show SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCc1cnc[nH]1 Show InChI InChI=1S/C14H16F3N3O3S/c15-14(16,17)23-12-4-6-13(7-5-12)24(21,22)20-8-2-1-3-11-9-18-10-19-11/h4-7,9-10,20H,1-3,8H2,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes				Bioorg Med Chem Lett 8: 2157-62 (1999) BindingDB Entry DOI: 10.7270/Q23T9GCZ
					More data for this Ligand-Target Pair