null
SMILES: C1CC1N1c2ncccc2C=Cc2cccnc12
InChI Key: InChIKey=MONPDXUIJPRGMZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50071365 (5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (K103N) | Bioorg Med Chem Lett 8: 2169-72 (1999) BindingDB Entry DOI: 10.7270/Q2028QP0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50071365 (5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (L1001) | Bioorg Med Chem Lett 8: 2169-72 (1999) BindingDB Entry DOI: 10.7270/Q2028QP0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50071365 (5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against HIV-1 wild type reverse transcriptase | Bioorg Med Chem Lett 8: 2169-72 (1999) BindingDB Entry DOI: 10.7270/Q2028QP0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50071365 (5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (L1001) | Bioorg Med Chem Lett 8: 2169-72 (1999) BindingDB Entry DOI: 10.7270/Q2028QP0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50071365 (5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (Y181C) | Bioorg Med Chem Lett 8: 2169-72 (1999) BindingDB Entry DOI: 10.7270/Q2028QP0 | |||||||||||
More data for this Ligand-Target Pair |