null
SMILES: Clc1ccc(CNC(=N)Cc2ccc(Cc3cnc[nH]3)cc2)cc1
InChI Key: InChIKey=QZLFLIRSGPJCFX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50071496 (CHEMBL73053 | N-(4-Chloro-benzyl)-2-[4-(1H-imidazo...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
De Novo Pharmaceuticals Curated by ChEMBL | Assay Description Ability to displace [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortex | J Med Chem 44: 1666-74 (2001) BindingDB Entry DOI: 10.7270/Q2WH2QP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50071496 (CHEMBL73053 | N-(4-Chloro-benzyl)-2-[4-(1H-imidazo...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of N-alpha-methylhistamine binding to histamine H3 receptor of guinea pig brain membranes | Bioorg Med Chem Lett 8: 2263-8 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WH3 | |||||||||||
More data for this Ligand-Target Pair |