BDBM50071734 (S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol-3-yl)-2-methyl-N-(1-pyridin-2-yl-cyclohexylmethyl)-propionamide::CHEMBL327678

SMILES: C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc(Cl)c(Cl)c1)C(=O)NCC1(CCCCC1)c1ccccn1

InChI Key: InChIKey=XVFAEENKHJXNNB-PMERELPUSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50071734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMBR (Homo sapiens (Human))	BDBM50071734 ((S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol...) Show SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc(Cl)c(Cl)c1)C(=O)NCC1(CCCCC1)c1ccccn1 Show InChI InChI=1S/C31H33Cl2N5O2/c1-30(18-21-19-35-26-10-4-3-9-23(21)26,38-29(40)37-22-12-13-24(32)25(33)17-22)28(39)36-20-31(14-6-2-7-15-31)27-11-5-8-16-34-27/h3-5,8-13,16-17,19,35H,2,6-7,14-15,18,20H2,1H3,(H,36,39)(H2,37,38,40)/t30-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells				Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4
					More data for this Ligand-Target Pair
GRPR (Homo sapiens (Human))	BDBM50071734 ((S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol...) Show SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc(Cl)c(Cl)c1)C(=O)NCC1(CCCCC1)c1ccccn1 Show InChI InChI=1S/C31H33Cl2N5O2/c1-30(18-21-19-35-26-10-4-3-9-23(21)26,38-29(40)37-22-12-13-24(32)25(33)17-22)28(39)36-20-31(14-6-2-7-15-31)27-11-5-8-16-34-27/h3-5,8-13,16-17,19,35H,2,6-7,14-15,18,20H2,1H3,(H,36,39)(H2,37,38,40)/t30-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.				Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4
					More data for this Ligand-Target Pair