BDBM50071813 CHEMBL2179992
SMILES: Cc1sc2nc(SCC(=O)c3ccc(O)c(O)c3)[nH]c(=O)c2c1C
InChI Key: InChIKey=FBFZQTVPMLIDPV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Krueppel-like factor 10 (Homo sapiens (Human)) | BDBM50071813 (CHEMBL2179992) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beth Israel Deaconess Medical Center Curated by ChEMBL | Assay Description Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d... | J Med Chem 58: 1466-78 (2015) Article DOI: 10.1021/jm5018187 BindingDB Entry DOI: 10.7270/Q2WM1G3D | |||||||||||
More data for this Ligand-Target Pair |