BDBM50071985 8-fluoro-1,3,3-trimethyl-9-nitro-4,11-dihydro-3H-indeno[2,1-f]quinoline::CHEMBL328804

SMILES: CC1=CC(C)(C)Nc2ccc-3c(Cc4cc(c(F)cc-34)[N+]([O-])=O)c12

InChI Key: InChIKey=OZWYSRUDBXCHMT-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50071985 (8-fluoro-1,3,3-trimethyl-9-nitro-4,11-dihydro-3H-i...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(Cc4cc(c(F)cc-34)[N+]([O-])=O)c12 |t:1| Show InChI InChI=1S/C19H17FN2O2/c1-10-9-19(2,3)21-16-5-4-12-13-8-15(20)17(22(23)24)7-11(13)6-14(12)18(10)16/h4-5,7-9,21H,6H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor-A (hPR-A)				Bioorg Med Chem Lett 8: 2731-6 (1999) BindingDB Entry DOI: 10.7270/Q2QF8S1M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50071985 (8-fluoro-1,3,3-trimethyl-9-nitro-4,11-dihydro-3H-i...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(Cc4cc(c(F)cc-34)[N+]([O-])=O)c12 |t:1| Show InChI InChI=1S/C19H17FN2O2/c1-10-9-19(2,3)21-16-5-4-12-13-8-15(20)17(22(23)24)7-11(13)6-14(12)18(10)16/h4-5,7-9,21H,6H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scientific Computing Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from Progesterone receptor				J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50071985 (8-fluoro-1,3,3-trimethyl-9-nitro-4,11-dihydro-3H-i...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(Cc4cc(c(F)cc-34)[N+]([O-])=O)c12 |t:1| Show InChI InChI=1S/C19H17FN2O2/c1-10-9-19(2,3)21-16-5-4-12-13-8-15(20)17(22(23)24)7-11(13)6-14(12)18(10)16/h4-5,7-9,21H,6H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against human progesterone receptor B (hPR-B) in cotransfected CV-1 cells				Bioorg Med Chem Lett 8: 2731-6 (1999) BindingDB Entry DOI: 10.7270/Q2QF8S1M
					More data for this Ligand-Target Pair