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BDBM50072014 6,9-difluoro-2,2,4-trimethyl-2,10-dihydro-1H-indeno[1,2-g]quinoline::CHEMBL327847

SMILES: CC1=CC(C)(C)Nc2cc3Cc4c(-c3cc12)c(F)ccc4F

InChI Key: InChIKey=PECGBIWHNLKBOG-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072014   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50072014
PNG
(6,9-difluoro-2,2,4-trimethyl-2,10-dihydro-1H-inden...)
Show SMILES CC1=CC(C)(C)Nc2cc3Cc4c(-c3cc12)c(F)ccc4F |t:1|
Show InChI InChI=1S/C19H17F2N/c1-10-9-19(2,3)22-17-7-11-6-14-15(20)4-5-16(21)18(14)13(11)8-12(10)17/h4-5,7-9,22H,6H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
3.10n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor-A (hPR-A)


Bioorg Med Chem Lett 8: 2731-6 (1999)


BindingDB Entry DOI: 10.7270/Q2QF8S1M
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50072014
PNG
(6,9-difluoro-2,2,4-trimethyl-2,10-dihydro-1H-inden...)
Show SMILES CC1=CC(C)(C)Nc2cc3Cc4c(-c3cc12)c(F)ccc4F |t:1|
Show InChI InChI=1S/C19H17F2N/c1-10-9-19(2,3)22-17-7-11-6-14-15(20)4-5-16(21)18(14)13(11)8-12(10)17/h4-5,7-9,22H,6H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 146n/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity against human progesterone receptor-A (hPR-A)


Bioorg Med Chem Lett 8: 2731-6 (1999)


BindingDB Entry DOI: 10.7270/Q2QF8S1M
More data for this
Ligand-Target Pair