BDBM50072021 2,2,4-Trimethyl-2,10-dihydro-1H-pyrido[2,3-b]carbazole::CHEMBL329339

SMILES: CC1=CC(C)(C)Nc2cc3[nH]c4ccccc4c3cc12

InChI Key: InChIKey=ZKBIYCLPMIOTJI-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50072021 (2,2,4-Trimethyl-2,10-dihydro-1H-pyrido[2,3-b]carba...) Show SMILES CC1=CC(C)(C)Nc2cc3[nH]c4ccccc4c3cc12 |t:1| Show InChI InChI=1S/C18H18N2/c1-11-10-18(2,3)20-17-9-16-14(8-13(11)17)12-6-4-5-7-15(12)19-16/h4-10,19-20H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scientific Computing Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from Progesterone receptor				J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50072021 (2,2,4-Trimethyl-2,10-dihydro-1H-pyrido[2,3-b]carba...) Show SMILES CC1=CC(C)(C)Nc2cc3[nH]c4ccccc4c3cc12 |t:1| Show InChI InChI=1S/C18H18N2/c1-11-10-18(2,3)20-17-9-16-14(8-13(11)17)12-6-4-5-7-15(12)19-16/h4-10,19-20H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor-A (hPR-A)				Bioorg Med Chem Lett 8: 2731-6 (1999) BindingDB Entry DOI: 10.7270/Q2QF8S1M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50072021 (2,2,4-Trimethyl-2,10-dihydro-1H-pyrido[2,3-b]carba...) Show SMILES CC1=CC(C)(C)Nc2cc3[nH]c4ccccc4c3cc12 |t:1| Show InChI InChI=1S/C18H18N2/c1-11-10-18(2,3)20-17-9-16-14(8-13(11)17)12-6-4-5-7-15(12)19-16/h4-10,19-20H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor-A (hPR-A)				Bioorg Med Chem Lett 8: 2731-6 (1999) BindingDB Entry DOI: 10.7270/Q2QF8S1M
					More data for this Ligand-Target Pair