BDBM50072135 CHEMBL3407918

SMILES: OC(=O)c1cc(ncn1)-c1ccc(N2CCCC2)c(Cl)c1

InChI Key: InChIKey=KYPSKXAYQTYOFI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kynurenine 3-monooxygenase (Homo sapiens (Human))	BDBM50072135 (CHEMBL3407918) Show SMILES OC(=O)c1cc(ncn1)-c1ccc(N2CCCC2)c(Cl)c1 Show InChI InChI=1S/C15H14ClN3O2/c16-11-7-10(3-4-14(11)19-5-1-2-6-19)12-8-13(15(20)21)18-9-17-12/h3-4,7-9H,1-2,5-6H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (U.K.) Ltd Curated by ChEMBL					Assay Description Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis				J Med Chem 58: 1159-83 (2015) Article DOI: 10.1021/jm501350y BindingDB Entry DOI: 10.7270/Q2445P5N
					More data for this Ligand-Target Pair
Kynurenine 3-monooxygenase (Homo sapiens (Human))	BDBM50072135 (CHEMBL3407918) Show SMILES OC(=O)c1cc(ncn1)-c1ccc(N2CCCC2)c(Cl)c1 Show InChI InChI=1S/C15H14ClN3O2/c16-11-7-10(3-4-14(11)19-5-1-2-6-19)12-8-13(15(20)21)18-9-17-12/h3-4,7-9H,1-2,5-6H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (U.K.) Ltd Curated by ChEMBL					Assay Description Inhibition of human KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis				J Med Chem 58: 1159-83 (2015) Article DOI: 10.1021/jm501350y BindingDB Entry DOI: 10.7270/Q2445P5N
					More data for this Ligand-Target Pair