null

SMILES: Fc1ccccc1SC(=N)C(C#N)C(C#N)C(=N)Sc1ccccc1F

InChI Key: InChIKey=CQZCGOIUHBLHBQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50072156 (2,3-Bis-[1-amino-1-(2-fluoro-phenylsulfanyl)-meth-...) Show SMILES Fc1ccccc1SC(=N)C(C#N)C(C#N)C(=N)Sc1ccccc1F Show InChI InChI=1S/C18H12F2N4S2/c19-13-5-1-3-7-15(13)25-17(23)11(9-21)12(10-22)18(24)26-16-8-4-2-6-14(16)20/h1-8,11-12,23-24H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Non-competitive inhibition of the dual specificity kinase MEK				Bioorg Med Chem Lett 8: 2839-44 (1999) BindingDB Entry DOI: 10.7270/Q2MW2HNN
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Homo sapiens (Human))	BDBM50072156 (2,3-Bis-[1-amino-1-(2-fluoro-phenylsulfanyl)-meth-...) Show SMILES Fc1ccccc1SC(=N)C(C#N)C(C#N)C(=N)Sc1ccccc1F Show InChI InChI=1S/C18H12F2N4S2/c19-13-5-1-3-7-15(13)25-17(23)11(9-21)12(10-22)18(24)26-16-8-4-2-6-14(16)20/h1-8,11-12,23-24H	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Ability to antagonise AP-1 transcriptional activity				Bioorg Med Chem Lett 8: 2839-44 (1999) BindingDB Entry DOI: 10.7270/Q2MW2HNN
					More data for this Ligand-Target Pair