null

SMILES: Clc1cccc(Cl)c1SC(=N)C(C#N)C(C#N)C(=N)Sc1c(Cl)cccc1Cl

InChI Key: InChIKey=KWHAKVNLIZXCJY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50072159 (2,3-Bis-[1-amino-1-(2,6-dichloro-phenylsulfanyl)-m...) Show SMILES Clc1cccc(Cl)c1SC(=N)C(C#N)C(C#N)C(=N)Sc1c(Cl)cccc1Cl Show InChI InChI=1S/C18H10Cl4N4S2/c19-11-3-1-4-12(20)15(11)27-17(25)9(7-23)10(8-24)18(26)28-16-13(21)5-2-6-14(16)22/h1-6,9-10,25-26H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Non-competitive inhibition of the dual specificity kinase MEK				Bioorg Med Chem Lett 8: 2839-44 (1999) BindingDB Entry DOI: 10.7270/Q2MW2HNN
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Homo sapiens (Human))	BDBM50072159 (2,3-Bis-[1-amino-1-(2,6-dichloro-phenylsulfanyl)-m...) Show SMILES Clc1cccc(Cl)c1SC(=N)C(C#N)C(C#N)C(=N)Sc1c(Cl)cccc1Cl Show InChI InChI=1S/C18H10Cl4N4S2/c19-11-3-1-4-12(20)15(11)27-17(25)9(7-23)10(8-24)18(26)28-16-13(21)5-2-6-14(16)22/h1-6,9-10,25-26H	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Ability to antagonise AP-1 transcriptional activity				Bioorg Med Chem Lett 8: 2839-44 (1999) BindingDB Entry DOI: 10.7270/Q2MW2HNN
					More data for this Ligand-Target Pair