null

SMILES: Cc1ccccc1SC(=N)C(C#N)C(C#N)C(=N)Sc1ccccc1C

InChI Key: InChIKey=NRMCWGBDXDBUKY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50072161 (2,3-Bis-[1-amino-1-o-tolylsulfanyl-meth-(Z)-yliden...) Show SMILES Cc1ccccc1SC(=N)C(C#N)C(C#N)C(=N)Sc1ccccc1C Show InChI InChI=1S/C20H18N4S2/c1-13-7-3-5-9-17(13)25-19(23)15(11-21)16(12-22)20(24)26-18-10-6-4-8-14(18)2/h3-10,15-16,23-24H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Non-competitive inhibition of the dual specificity kinase MEK				Bioorg Med Chem Lett 8: 2839-44 (1999) BindingDB Entry DOI: 10.7270/Q2MW2HNN
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Homo sapiens (Human))	BDBM50072161 (2,3-Bis-[1-amino-1-o-tolylsulfanyl-meth-(Z)-yliden...) Show SMILES Cc1ccccc1SC(=N)C(C#N)C(C#N)C(=N)Sc1ccccc1C Show InChI InChI=1S/C20H18N4S2/c1-13-7-3-5-9-17(13)25-19(23)15(11-21)16(12-22)20(24)26-18-10-6-4-8-14(18)2/h3-10,15-16,23-24H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Ability to antagonise AP-1 transcriptional activity				Bioorg Med Chem Lett 8: 2839-44 (1999) BindingDB Entry DOI: 10.7270/Q2MW2HNN
					More data for this Ligand-Target Pair