BDBM50072171 (1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-methyl-cyclopropanecarboxylic acid::CHEMBL97574

SMILES: C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O

InChI Key: InChIKey=VYTOVCNIMJIGDL-FPNSYFSOSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50072171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50072171 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C21H21NO5/c1-11-17(19(23)24)18(11)21(22,20(25)26)10-14-12-6-2-4-8-15(12)27-16-9-5-3-7-13(14)16/h2-9,11,14,17-18H,10,22H2,1H3,(H,23,24)(H,25,26)/t11-,17+,18+,21?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 1 (mGluR1) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50072171 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C21H21NO5/c1-11-17(19(23)24)18(11)21(22,20(25)26)10-14-12-6-2-4-8-15(12)27-16-9-5-3-7-13(14)16/h2-9,11,14,17-18H,10,22H2,1H3,(H,23,24)(H,25,26)/t11-,17+,18+,21?/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 4 (mGluR4) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50072171 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C21H21NO5/c1-11-17(19(23)24)18(11)21(22,20(25)26)10-14-12-6-2-4-8-15(12)27-16-9-5-3-7-13(14)16/h2-9,11,14,17-18H,10,22H2,1H3,(H,23,24)(H,25,26)/t11-,17+,18+,21?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 5 (mGluR5) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
GRM8 (Homo sapiens (Human))	BDBM50072171 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C21H21NO5/c1-11-17(19(23)24)18(11)21(22,20(25)26)10-14-12-6-2-4-8-15(12)27-16-9-5-3-7-13(14)16/h2-9,11,14,17-18H,10,22H2,1H3,(H,23,24)(H,25,26)/t11-,17+,18+,21?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072171 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C21H21NO5/c1-11-17(19(23)24)18(11)21(22,20(25)26)10-14-12-6-2-4-8-15(12)27-16-9-5-3-7-13(14)16/h2-9,11,14,17-18H,10,22H2,1H3,(H,23,24)(H,25,26)/t11-,17+,18+,21?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
GRM7 (Homo sapiens (Human))	BDBM50072171 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C21H21NO5/c1-11-17(19(23)24)18(11)21(22,20(25)26)10-14-12-6-2-4-8-15(12)27-16-9-5-3-7-13(14)16/h2-9,11,14,17-18H,10,22H2,1H3,(H,23,24)(H,25,26)/t11-,17+,18+,21?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair