null

SMILES: COc1cc2nc(C)nc(-c3cc(OCC4CC4)cc(OCC4CC4)c3)c2cc1OC

InChI Key: InChIKey=NEBKNEPHIHFRHN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (RAT)	BDBM50072206 (4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6,7-dimethox...) Show SMILES COc1cc2nc(C)nc(-c3cc(OCC4CC4)cc(OCC4CC4)c3)c2cc1OC Show InChI InChI=1S/C25H28N2O4/c1-15-26-22-12-24(29-3)23(28-2)11-21(22)25(27-15)18-8-19(30-13-16-4-5-16)10-20(9-18)31-14-17-6-7-17/h8-12,16-17H,4-7,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4B.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50072206 (4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6,7-dimethox...) Show SMILES COc1cc2nc(C)nc(-c3cc(OCC4CC4)cc(OCC4CC4)c3)c2cc1OC Show InChI InChI=1S/C25H28N2O4/c1-15-26-22-12-24(29-3)23(28-2)11-21(22)25(27-15)18-8-19(30-13-16-4-5-16)10-20(9-18)31-14-17-6-7-17/h8-12,16-17H,4-7,13-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4D.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50072206 (4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6,7-dimethox...) Show SMILES COc1cc2nc(C)nc(-c3cc(OCC4CC4)cc(OCC4CC4)c3)c2cc1OC Show InChI InChI=1S/C25H28N2O4/c1-15-26-22-12-24(29-3)23(28-2)11-21(22)25(27-15)18-8-19(30-13-16-4-5-16)10-20(9-18)31-14-17-6-7-17/h8-12,16-17H,4-7,13-14H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4A.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair