BDBM50072255 (E)-4-(3,4-Difluoro-phenyl)-4-oxo-but-2-enoic acid::CHEMBL98775

SMILES: OC(=O)\C=C\C(=O)c1ccc(F)c(F)c1

InChI Key: InChIKey=VXEIUAVCQAVVOW-ONEGZZNKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kynurenine 3-monooxygenase (Rattus norvegicus)	BDBM50072255 ((E)-4-(3,4-Difluoro-phenyl)-4-oxo-but-2-enoic acid...) Show SMILES OC(=O)\C=C\C(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C10H6F2O3/c11-7-2-1-6(5-8(7)12)9(13)3-4-10(14)15/h1-5H,(H,14,15)/b4-3+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia& Upjohn Curated by ChEMBL					Assay Description Inhibition of rat liver KYN 3-OHase.				Bioorg Med Chem Lett 8: 2907-12 (1999) BindingDB Entry DOI: 10.7270/Q23X874K
					More data for this Ligand-Target Pair
Kynurenine 3-monooxygenase (Rattus norvegicus)	BDBM50072255 ((E)-4-(3,4-Difluoro-phenyl)-4-oxo-but-2-enoic acid...) Show SMILES OC(=O)\C=C\C(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C10H6F2O3/c11-7-2-1-6(5-8(7)12)9(13)3-4-10(14)15/h1-5H,(H,14,15)/b4-3+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia& Upjohn Curated by ChEMBL					Assay Description Inhibition of rat brain KYN 3-OHase.				Bioorg Med Chem Lett 8: 2907-12 (1999) BindingDB Entry DOI: 10.7270/Q23X874K
					More data for this Ligand-Target Pair