BDBM50072518 (6S,8aS)-6-[4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-4-oxo-hexahydro-pyrrolo[1,2-a]pyrazine-2-carboxylic acid benzyl ester::CHEMBL322307
SMILES: NC(=N)NCCCC(NC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)C(=O)OCc1ccccc1)C(=O)c1nccs1
InChI Key: InChIKey=BNLHSTXGBMVOTB-JVUMBYKBSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50072518 ((6S,8aS)-6-[4-Guanidino-1-(thiazole-2-carbonyl)-bu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BioChem Therapeutic Inc. Curated by ChEMBL | Assay Description Binding affinity of the compound against thrombin | Bioorg Med Chem Lett 8: 3193-8 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NGF | |||||||||||
More data for this Ligand-Target Pair |