BDBM50072779 (E)-7-{4-[4-(2-Phenoxy-ethylcarbamoyl)-oxazol-2-yl]-phenyl}-7-pyridin-3-yl-hept-6-enoic acid::CHEMBL151083

SMILES: OC(=O)CCCC\C=C(/c1ccc(cc1)-c1nc(co1)C(=O)NCCOc1ccccc1)c1cccnc1

InChI Key: InChIKey=SXIFZKGCEZUKRA-KBKYJPHKSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50072779 ((E)-7-{4-[4-(2-Phenoxy-ethylcarbamoyl)-oxazol-2-yl...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(cc1)-c1nc(co1)C(=O)NCCOc1ccccc1)c1cccnc1 Show InChI InChI=1S/C30H29N3O5/c34-28(35)12-6-2-5-11-26(24-8-7-17-31-20-24)22-13-15-23(16-14-22)30-33-27(21-38-30)29(36)32-18-19-37-25-9-3-1-4-10-25/h1,3-4,7-11,13-17,20-21H,2,5-6,12,18-19H2,(H,32,36)(H,34,35)/b26-11+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro for inhibitory activity against thromboxane synthase				J Med Chem 41: 5362-74 (1999) Article DOI: 10.1021/jm980173n BindingDB Entry DOI: 10.7270/Q2V123Z8
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50072779 ((E)-7-{4-[4-(2-Phenoxy-ethylcarbamoyl)-oxazol-2-yl...) Show SMILES OC(=O)CCCC\C=C(/c1ccc(cc1)-c1nc(co1)C(=O)NCCOc1ccccc1)c1cccnc1 Show InChI InChI=1S/C30H29N3O5/c34-28(35)12-6-2-5-11-26(24-8-7-17-31-20-24)22-13-15-23(16-14-22)30-33-27(21-38-30)29(36)32-18-19-37-25-9-3-1-4-10-25/h1,3-4,7-11,13-17,20-21H,2,5-6,12,18-19H2,(H,32,36)(H,34,35)/b26-11+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	74.3	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro for antagonistic activity against thromboxane synthase receptor				J Med Chem 41: 5362-74 (1999) Article DOI: 10.1021/jm980173n BindingDB Entry DOI: 10.7270/Q2V123Z8
					More data for this Ligand-Target Pair