BDBM50072787 (E)-7-(4-{4-[3-(1-Cyclohexyl-ethoxy)-propylcarbamoyl]-oxazol-2-yl}-phenyl)-7-pyridin-3-yl-hept-6-enoic acid::CHEMBL150206
SMILES: CC(OCCCNC(=O)c1coc(n1)-c1ccc(cc1)C(=C/CCCCC(O)=O)\c1cccnc1)C1CCCCC1
InChI Key: InChIKey=VDSYMHSEFRKHET-VFLNYLIXSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50072787 ((E)-7-(4-{4-[3-(1-Cyclohexyl-ethoxy)-propylcarbamo...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro for inhibitory activity against thromboxane synthase | J Med Chem 41: 5362-74 (1999) Article DOI: 10.1021/jm980173n BindingDB Entry DOI: 10.7270/Q2V123Z8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50072787 ((E)-7-(4-{4-[3-(1-Cyclohexyl-ethoxy)-propylcarbamo...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 58.2 | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro for antagonistic activity against thromboxane synthase receptor | J Med Chem 41: 5362-74 (1999) Article DOI: 10.1021/jm980173n BindingDB Entry DOI: 10.7270/Q2V123Z8 | |||||||||||
More data for this Ligand-Target Pair |