BDBM50072805 4-[3-(4-Carbamoyl-furazan-3-ylmethoxy)-phenyl]-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester::CHEMBL151273

SMILES: COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C(N)=O)c1

InChI Key: InChIKey=LGIPAEXJOYCURB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cav1.3/Cav beta3/Cav alpha2delta complex (Rattus norvegicus)	BDBM50072805 (4-[3-(4-Carbamoyl-furazan-3-ylmethoxy)-phenyl]-2,6...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C(N)=O)c1 |c:13,t:10| Show InChI InChI=1S/C21H22N4O7/c1-10-15(20(27)29-3)17(16(11(2)23-10)21(28)30-4)12-6-5-7-13(8-12)31-9-14-18(19(22)26)25-32-24-14/h5-8,15,17H,9H2,1-4H3,(H2,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Cav1.3/Cav beta3/Cav alpha2delta complex (Rattus norvegicus)	BDBM50072805 (4-[3-(4-Carbamoyl-furazan-3-ylmethoxy)-phenyl]-2,6...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C(N)=O)c1 |c:13,t:10| Show InChI InChI=1S/C21H22N4O7/c1-10-15(20(27)29-3)17(16(11(2)23-10)21(28)30-4)12-6-5-7-13(8-12)31-9-14-18(19(22)26)25-32-24-14/h5-8,15,17H,9H2,1-4H3,(H2,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair