BDBM50072817 4-[3-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester::CHEMBL151447

SMILES: COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C#N)c1)C(=[OH+])OC

InChI Key: InChIKey=BGDKOOCJAOSEEX-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cav1.3/Cav beta3/Cav alpha2delta complex (Rattus norvegicus)	BDBM50072817 (4-[3-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C#N)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-6-5-7-14(8-13)31-10-15-16(9-22)25(28)32-24-15/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Cav1.3/Cav beta3/Cav alpha2delta complex (Rattus norvegicus)	BDBM50072817 (4-[3-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C#N)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-6-5-7-14(8-13)31-10-15-16(9-22)25(28)32-24-15/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair