BDBM50072996 3-[5-((E)-2-Diethylcarbamoyl-1-methyl-vinyl)-2-(1-phenyl-ethoxy)-phenyl]-propionic acid::CHEMBL49866
SMILES: CCN(CC)C(=O)\C=C(/C)c1ccc(OC(C)c2ccccc2)c(CCC(O)=O)c1
InChI Key: InChIKey=PIZMCCZVZJVIPB-FBMGVBCBSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50072996 (3-[5-((E)-2-Diethylcarbamoyl-1-methyl-vinyl)-2-(1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharmaceuticals Corporation Curated by ChEMBL | Assay Description Leukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNs | J Med Chem 42: 164-72 (1999) Article DOI: 10.1021/jm980540v BindingDB Entry DOI: 10.7270/Q26972QG | |||||||||||
More data for this Ligand-Target Pair |