BDBM50073048 2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-N-(9-oxo-9H-fluoren-3-yl)-acetamide::CHEMBL62166
SMILES: O=C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)Nc1ccc2C(=O)c3ccccc3-c2c1
InChI Key: InChIKey=ZWPVDHAWHOQDPJ-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NPY1R (RAT) | BDBM50073048 (2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description The compound was tested for the binding affinity against NPY1 (Neuropeptide Y receptor type 1) | J Med Chem 42: 181-201 (1999) Article DOI: 10.1021/jm980521l BindingDB Entry DOI: 10.7270/Q2T43S8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NPY2R (RAT) | BDBM50073048 (2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description The compound was tested for the binding affinity against Neuropeptide Y receptor type 2 | J Med Chem 42: 181-201 (1999) Article DOI: 10.1021/jm980521l BindingDB Entry DOI: 10.7270/Q2T43S8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human)) | BDBM50073048 (2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity of the compound against human Neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligand | Bioorg Med Chem Lett 11: 2283-6 (2001) BindingDB Entry DOI: 10.7270/Q2NZ86WB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PPYR1 (RAT) | BDBM50073048 (2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description The compound was tested for the binding affinity against Neuropeptide Y receptor type 4 | J Med Chem 42: 181-201 (1999) Article DOI: 10.1021/jm980521l BindingDB Entry DOI: 10.7270/Q2T43S8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human)) | BDBM50073048 (2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in rat | J Med Chem 42: 181-201 (1999) Article DOI: 10.1021/jm980521l BindingDB Entry DOI: 10.7270/Q2T43S8P | |||||||||||
More data for this Ligand-Target Pair |