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SMILES: CN1CCN(CC1)C1c2ccc(Cl)cc2CCc2cccnc12

InChI Key: InChIKey=VUQLWEZYDIEMAG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073184   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(RAT)		BDBM50073184
PNG
(8-Chloro-11-(4-methyl-piperazin-1-yl)-6,11-dihydro...)
Show SMILES CN1CCN(CC1)C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C19H22ClN3/c1-22-9-11-23(12-10-22)19-17-7-6-16(20)13-15(17)5-4-14-3-2-8-21-18(14)19/h2-3,6-8,13,19H,4-5,9-12H2,1H3
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 6.5n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against Histamine H1 receptor using receptor binding assay in rat brain membranes

Bioorg Med Chem Lett 8: 3469-74 (1999)


BindingDB Entry DOI: 10.7270/Q21J98X8
More data for this
Ligand-Target Pair