null
SMILES: O[C@H]1[C@@H](Cc2ccccc2)N(Cc2ccc3[nH]ncc3c2)C(=O)N2[C@@H]3CC[C@]2(C[C@H]3OCc2ccccc2)[C@H]1O
InChI Key: InChIKey=GXHKBYHBPCOSML-KAHMAFICSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50073327 ((1S,2R,3S,4R,8R,9R)-4-Benzyl-9-benzyloxy-2,3-dihyd...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLC | Bioorg Med Chem Lett 8: 3615-20 (1999) BindingDB Entry DOI: 10.7270/Q2VX0FP1 | |||||||||||
More data for this Ligand-Target Pair |