BDBM50073331 (2Z,4Z)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-penta-2,4-dienoic acid (1,2,2,6,6-pentamethyl-piperidin-4-yl)-amide::CHEMBL121126::TCMDC-139106
SMILES: CO\C(=C/C=C\c1cc2cc(Cl)c(Cl)cc2[nH]1)C(=O)NC1CC(C)(C)N(C)C(C)(C)C1
InChI Key: InChIKey=NAQKKRDQKSXZSM-DQUVZLBQSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50073331 ((2Z,4Z)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 663 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Research Unit Curated by ChEMBL | Assay Description Compound was measured for the inhibition of bafilomycin-sensitive ATPase activity in partially purified membrane preparation from chicken osteoclast ... | Bioorg Med Chem Lett 8: 3621-6 (1999) BindingDB Entry DOI: 10.7270/Q2R49PXM | |||||||||||
More data for this Ligand-Target Pair |