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SMILES: C[C@H]1CN(Cc2cccc(\C=C\c3n[nH]c4cc(ccc34)[C@@H]3C[C@@]33C(=O)Nc4ccccc34)c2)C[C@@H](C)O1

InChI Key: InChIKey=AXZZLIJZGQLQEJ-WKNQAKRMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073546   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PLK4


(Homo sapiens (Human))		BDBM50073546
PNG
(CHEMBL3408950)
Show SMILES C[C@H]1CN(Cc2cccc(\C=C\c3n[nH]c4cc(ccc34)[C@@H]3C[C@@]33C(=O)Nc4ccccc34)c2)C[C@@H](C)O1 |r|
Show InChI InChI=1S/C32H32N4O2/c1-20-17-36(18-21(2)38-20)19-23-7-5-6-22(14-23)10-13-28-25-12-11-24(15-30(25)35-34-28)27-16-32(27)26-8-3-4-9-29(26)33-31(32)37/h3-15,20-21,27H,16-19H2,1-2H3,(H,33,37)(H,34,35)/b13-10+/t20-,21+,27-,32-/m0/s1
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PLK4 (unknown origin) by ELISA

J Med Chem 58: 147-69 (2015)


BindingDB Entry DOI: 10.7270/Q2M0475V
More data for this
Ligand-Target Pair